Chromosomes


   
 
Summary
 
Chromosomes are tiny thread-like structures found in the nucleus of a cell.
 
Chromosomes store and transmit the coded information which is responsible for all the life processes of an organism. Hence, chromosomes are commonly described as carriers of heredity.
 
In bacteria, the entire hereditary material is packed into a single, irregularly packed, compact mass called nucleioid or bacterial chromosome.
 
Bacterial chromosomes lack a nuclear membrane and are not associated with histones.
 
Eukaryotic chromosomes are visible only during metaphase stage of mitosis.
 
The chromosome number of a given species is generally described as the diploid number (2n) since chromosomes occur in pairs.
 
Haploid number of chromosomes occur in gametes and spores. Some adult organisms (chlamydomonos, male honey bee) have haploid number of chromosomes.
 
Chromosomes range in size from 0.1 to 30 mm in length and 0.2 to 2.0 mm in thickness. When the number is less, the chromosomes are larger in size.
 
A metaphase chromosome shows two identical components called chromatids, joined by a centromere (primary constriction). Each chromatid has two arms.
 
A secondary constriction may occur sometimes. Such a chromosome is called sat-chromosome.
 
Chemically the chromosome is composed of nucleoproteins present in the form of a highly coiled chromonema.
 
Chromonema is composed of a chain of bead-like structures called nucleosomes (nu bodies).
 
A nucleosome has a core particle formed by proteins called histones surrounded by a DNA strand.
 
The part of DNA not associated with histones is called Linker DNA.
 
Normally a chromosome has only one centromere (monocentric). It can be sometimes dicentric or polycentric. Very rarely it may lack a centromere (acentric).
 
Monocentric chromosome can be distinguished into metacentric, submetacentric, acrocentric and telocentric, based on the position of centromere.
 
Chromosomes, which are extremely larger than the normal ones are called giant chromosomes. They occur in some animal cells.
 
Lampbrush chromosomes of amphibian oocytes and polytene chromosomes of Drosophile one common examples of giant chromosomes.
 
Genome is the term used to describe the sum total of all the genes present in a haploid set of chromosomes.
 
In unisexual organisms the chromosomes can be distinguished into autosomes (somatic chromosomes) and allosomes (sex chromosomes).
 
Allosomes have a role in sex-determination and in the expression of sex-linked characters.
 
 
     
   
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