The plasma b - cells produce a lot of anti-bodies, which circulate in the lymph. Each person can make 107to 108 different kinds of antibody molecules so that there is an antibody for any antigen.
The plasma membrane of each B cell should be sensitised by contact with a specific antigen for the release of antibodies. The plasma cells do not migrate to the site of infection but act through the lymph. So they form the humoral immune system. The B lymphocytes are short lived and are replaced every few days from the bone marrow.
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