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This theory describes the effect of fixed or non-diffusible ions which mostly accumulate on the inner surface of the outer membrane. Process is named after its discoverer F.G.Donnan. If there is a negative non-diffusing charge on one side of a membrane, it will create a potential gradient across the membrane from which ions will diffuse. The result will be an electrochemical equilibrium. The concentration (chemical potential) of ions will not necessarily be the bsame inside and outside. Thus, as an electrical disequilibrium is maintained because of diffusing charges. A concentration disequilibrium is established. |