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Changes in brain
Brain can be damaged by- head injuries
- infections such as meningitis, measles, encephalitis
- cerebral arteriosclerosis
- psychotropic drugs like sedatives, hallucinations, barbiturates
- nutritional deficiencies like vitamins, iodine
- Diseases like tuberculosis, leprosy
- Toxic substances like CS2, Hg, Pb, Sn, Mn, etc.
- Radiations during development of nervous system.
Major Categories of Psychotropic Drugs, their Effects and Clinical Uses
| Type of drug | Examples | Effects | Clinical use |
|---|---|---|---|
| Sedatives and tranquilisers (depressant) | Barbiturates Benzodiazepines (e.g., Valium) | Depress brain activity and produces feelings of calmness, relaxation, drowsiness and deep sleep (high doses) | Hypnotic antianxiety |
| Opiate narcoitics | Opium, morphine, heroin, pethidine, methadone | Suppress brain function, relieve intense pain (physical and mental), produce temporary euphoria | Analgesic |
| Stimulants | Caffeine (very mild), amphetamines (including dexamphetamine, cocaine and its derivative Novacaine) | Stimulate the nervous system; make a person more wakeful, increase alertness and activity, produce excite ment | Attention deficit, Narcolepsy, Weight control |
| Hallucinogens | LSD, mescaline, psilocybin, charas, hashish, marijuana (bhang) | Alter thought, feelings and perceptions; hallucinations | None |

