Antigens
The foreign matter that enters the body and elicits a specific immune response by lymphocytes is an antigen (anti - antibody gen - generating) It stimulates the immune system to produce protective chemicals or special cells to destroy the antigens. These protective che..
Antigens
An antigen is any chemical substance that, when introduced into the body, causes the body to produce specific antibodies, which can react with the antigen. Chemically a vast majority of antigens are proteins , nucleoproteins, lipo proteins etc. The entire bac..
Antibodies
Monoclonal antibodies are pure, high affinity, antigen specific, proteinaceous bodies derived outside the organism from clonal cultures of hybrid cells called hybridoma..
Antibodies
Monoclonal antibodies are pure, high affinity, antigen specific, proteinaceous bodies derived outside the organism from clonal cultures of hybrid cells called hybridomas. Being very specific and reproducible, antibodies are able to be conjugated to toxic drugs and inje..
Antibodies
An antibody is a protein produced by the body in response to the presence of an antigen. Anti bodies belong to a group of proteins called globulins and they are also known as Immunoglobulins (Ig..
Antibody - mediated immunity
Antibodies are proteins. Most antibodies contain 4 pairs of polypeptide chains. Two of the chains are identical to each other and are called Heavy chains or H chains and they are long chains. the other 2 chains, also identical to each other, are called Light or L chains and..
Organ Transplants and Antibodies
Organ transplantation is defined as the transfer of organs (like kidneys, heart liver etc) from one person to another. An organ transplant always involves a donor - who donates an organ and a recipient - who receives the organ. For an organ transplantation, the donor and the recipient should be gen..
Diagnostic Kits - Enzyme - Linked Immunosorbent Assay (ELISA)
ELISA technique is widely used for the detection of viruses, fungi, bacteria etc. It is a very sensitive and specific test and needs a very small amount of reagents. It is used to detect the infectious diseases like tuberculosis, AIDS etc. The diagnostic kit detects the presence of an antigenh..
Humoral Immune System
The plasma b - cells produce a lot of anti-bodies, which circulate in the lymph. Each person can make 10 7 to 10 8 different kinds of antibody molecules so that there is an antibody for any antigen. The plasma membrane of each B cell should be sensitised by c..
The procedure
The antibody, which is specific to the antigen to be detected must be present in the kit. The sample, which is suspected to contain the antigen is immobilised on the ELISA plate. The specific anti body is added and allowed to react with the antigen. Washing ..
Result
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